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5
10
15
20
2 months
1 year
2 years
Mouse age
Number of sorted
microglia (x10
4
)
Genotype
WT
Het
KO
1153
419
893
WT
KO
-5
0
5
-5
0
5
10
PC1: 29% variance
PC2: 17% variance
Gender
F
M
Genotype
WT
Het
KO
Age
2yr
-10
-5
0
5
10
PC2: 17% variance
-10
-5
0
5
-10
0
10
20
PC1: 32% variance
PC3: 11% variance
Gender
F
M
Genotype
WT
Het
KO
Age
2mo
1yr
2yr